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CryoEM micrographs of slipper limpet (Crepidula fornicata) hemocyanin

ABSTRACT:

SUBMITTER: Mark Thomas Young

PROVIDER: EMPIAR-11554 | biostudies-other |

REPOSITORIES: biostudies-other

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CryoEM structure and Alphafold molecular modelling of a novel molluscan hemocyanin.

Pasqualetto Gaia G Mack Andrew A Lewis Emily E Cooper Ryan R Holland Alistair A Borucu Ufuk U Mantell Judith J Davies Tom T Weckener Miriam M Clare Dan D Green Tom T Kille Pete P Muhlhozl Alex A Young Mark T MT

PloS one 20230622 6

Hemocyanins are multimeric oxygen transport proteins present in the blood of arthropods and molluscs, containing up to 8 oxygen-binding functional units per monomer. In molluscs, hemocyanins are assembled in decamer 'building blocks' formed of 5 dimer 'plates', routinely forming didecamer or higher-order assemblies with d5 or c5 symmetry. Here we describe the cryoEM structures of the didecamer (20-mer) and tridecamer (30-mer) forms of a novel hemocyanin from the slipper limpet Crepidula fornicat ...[more]

PMID: 37347755

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