Cryo-EM of Tulane virus Inverted contrast
Ontology highlight
ABSTRACT:
SUBMITTER: Chen Sun
PROVIDER: EMPIAR-12021 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
The 2.6 Å Structure of a Tulane Virus Variant with Minor Mutations Leading to Receptor Change.
Sun Chen C Huang Pengwei P Xu Xueyong X Vago Frank S FS Li Kunpeng K Klose Thomas T Jiang Xi Jason XJ Jiang Wen W
Biomolecules 20240116 1
Human noroviruses (HuNoVs) are a major cause of acute gastroenteritis, contributing significantly to annual foodborne illness cases. However, studying these viruses has been challenging due to limitations in tissue culture techniques for over four decades. Tulane virus (TV) has emerged as a crucial surrogate for HuNoVs due to its close resemblance in amino acid composition and the availability of a robust cell culture system. Initially isolated from rhesus macaques in 2008, TV represents a novel ...[more]
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