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Single particle dataset of respiratory complex I from Paracoccus dentrificans in MSP2N2 nanodiscs


ABSTRACT:

SUBMITTER: Judy Hirst 

PROVIDER: EMPIAR-12077 | biostudies-other |

REPOSITORIES: biostudies-other

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Publications

Structure of the turnover-ready state of an ancestral respiratory complex I.

Ivanov Bozhidar S BS   Bridges Hannah R HR   Jarman Owen D OD   Hirst Judy J  

Nature communications 20241029 1


Respiratory complex I is pivotal for cellular energy conversion, harnessing energy from NADH:ubiquinone oxidoreduction to drive protons across energy-transducing membranes for ATP synthesis. Despite detailed structural information on complex I, its mechanism of catalysis remains elusive due to lack of accompanying functional data for comprehensive structure-function analyses. Here, we present the 2.3-Å resolution structure of complex I from the α-proteobacterium Paracoccus denitrificans, a close  ...[more]

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