ADAM-28: A potential oncogene involved in asbestos-related lung adenocarcinomas

ABSTRACT: To identify gene expression biomarkers associated with asbestos-related lung adenocarcinoma, we analyzed primary tumour gene expression for a total of 36 primary lung adenocarcinomas on 22,323 element microarrays, comparing 12 patients with lung asbestos body counts above levels associated with urban dwelling (ARLC-AC: asbestos-related lung cancer-adenocarcinoma) with 24 patients with no asbestos bodies (NARLC-AC: non-asbestos related lung cancer-adenocarcinoma). To identify gene expression biomarkers associated with asbestos-related lung tumorigenicity, we performed gene expression array analysis on tumours of 36 patients with primary lung adenocarcinoma, comparing twelve patients with lung asbestos body counts above levels associated with urban dwelling (ARLC-AC: asbestos-related lung ca

ORGANISM(S): Homo sapiens

SUBMITTER: Wright CM 

PROVIDER: S-ECPF-GEOD-20875 | biostudies-other | 2010 Aug

REPOSITORIES: biostudies-other