Unknown

Dataset Information

0

Knock-down and Over-expression of JMJD6 in MCF-7 and/or MDA-MB231


ABSTRACT: By survival analysis of breast cancer patients, JMJD6 was found to be significantly associated with poor prognosis. Over-expression and knock-down of JMJD6 in breast cancer cell lines suggested a role in proliferation. In order to study the transcriptional events that occur following JMJD6 expression changes, siRNA-mediated knock-down of JMJD6 was performed in MCF-7 and MDA-MB231 and stable over-expression of JMJD6 was performed in MCF-7. There are 2 different siRNA-mediated knock-downs of JMJD6 with 2 biological replicates in MCF-7 and MDA-MB231; 3 clones of JMJD6 over-expression with 3 biological replicates in MCF-7. The control for the knock-downs is scrambled siRNA-treated MCF-7 and MDA-MB231 and the control for JMJD6 over-expression is empty vector over-expression in MCF-7.

ORGANISM(S): Homo sapiens

SUBMITTER: Lee YF 

PROVIDER: S-ECPF-GEOD-31782 | biostudies-other | 2012

REPOSITORIES: biostudies-other

Similar Datasets

2012-05-10 | GSE31782 | GEO
2012-05-09 | E-GEOD-31782 | biostudies-arrayexpress
| S-EPMC7352455 | biostudies-literature
| S-EPMC4769841 | biostudies-literature
| S-EPMC7068580 | biostudies-literature
| S-EPMC9983172 | biostudies-literature
| S-ECPF-GEOD-34925 | biostudies-other
| S-EPMC4186755 | biostudies-other
2020-06-22 | PXD017721 | Pride
| S-ECPF-MEXP-3547 | biostudies-other