Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

LM2 cell: infected with lentivirus to stably express Elf5 vs GFP

ABSTRACT: Elf5 induced transcriptional changes in high lung metastasis subline LM2 (MDA-MB-231 origin), control (GFP) vs ELF5 Two-condition experiment, control (GFP) vs Elf5. Each has duplicate biological repeats.

ORGANISM(S): Homo sapiens

SUBMITTER: Wei Yong

PROVIDER: S-ECPF-GEOD-32143 | biostudies-other |

REPOSITORIES: biostudies-other

ACCESS DATA

Json Xml

Similar Datasets

LM2 cell: infected with lentivirus to stably express Elf5 vs GFP

Project description:Elf5 induced transcriptional changes in high lung metastasis subline LM2 (MDA-MB-231 origin), control (GFP) vs ELF5

2012-09-20 | GSE32143 | GEO

LM2 cell: infected with lentivirus to stably express Elf5 vs GFP

Project description:Elf5 induced transcriptional changes in high lung metastasis subline LM2 (MDA-MB-231 origin), control (GFP) vs ELF5 Two-condition experiment, control (GFP) vs Elf5. Each has duplicate biological repeats.

2012-09-20 | E-GEOD-32143 | biostudies-arrayexpress

MDA-MB-231 cell: infected with lentivirus to stably express mut-Elf5 vs WT-Elf5

Project description:Elf5 induced transcriptional changes in MDA-MB-231 origin, control (mut Elf5) vs WT ELF5 Two-condition experiment, control (mut-Elf5) vs WT-Elf5. Each has 3 biological repeats.

| S-ECPF-GEOD-32144 | biostudies-other

MDA-MB-231 cell: infected with lentivirus to stably express mut-Elf5 vs WT-Elf5

Project description:Elf5 induced transcriptional changes in MDA-MB-231 origin, control (mut Elf5) vs WT ELF5

2012-09-20 | GSE32144 | GEO

MDA-MB-231 cell: infected with lentivirus to stably express mut-Elf5 vs WT-Elf5

2012-09-20 | E-GEOD-32144 | biostudies-arrayexpress

Human breast cancer LM2 cell lines: control vs. MTDH knockdown

Project description:Transcriptional profiling of human breast cancer cell line LM2, a subline of MDA-MB-231 highly metastatic to lung when injected to nude mice, to identify the genes that are regulated after the metastasis gene metadherin is knocked down. Keywords: Genetic modification Empty pSuper vector control cells were compared to the cells transfected with the MTDH knockdown shRNA construct. Two cultured conditions were studied: the LM2 cancer cells were cultured alone or on top of a monolayer of human lung endothelial HMVEC-L cells. Three arrays for each sample.

| S-ECPF-GEOD-9187 | biostudies-other

A new Elf5Cre ERT 2- GFP BAC transgenic mouse model for tracing Elf5 cell lineages in adult tissues.

Project description:Elf5 is a transcription factor known to regulate critical developmental processes and has been shown to act as a tumour suppressor in multiple cancers. Elf5 knockout mice are embryonically lethal, limiting in vivo studies pertaining to its function. Moreover, haploinsufficiency of Elf5 limits the use of current mouse models to investigate adult tissue distribution of Elf5. Here, we successfully generated Elf5Cre ERT 2- GFP bacterial artificial chromosome (BAC) transgenic mice and show that Elf5+ cells are present in several adult tissues, where its expression was previously not known. Our study demonstrates the unique distribution of Elf5+ cells in multiple adult organs, which will facilitate future studies investigating the function of Elf5 in these tissues during homeostasis, repair and cancer.

| S-EPMC6538489 | biostudies-literature

Expression profiling of QSG-7701 cells: stably express lncRNA-PRAL vs control

Project description:lncRNA-PRAL induced transcriptional changes in QSG-7701

2017-11-24 | GSE63598 | GEO

Expression profiling of SMMC-7721 cells: stably express lncRNA-PRAL vs control

Project description:lncRNA-PRAL induced transcriptional changes in SMMC-7721

2017-11-24 | GSE63599 | GEO

Expression profiling of SMMC-7721 cells: stably express lncRNA-ATB vs pcDNA3.1

Project description:lncRNA-ATB induced transcriptional changes in SMMC-7721

2014-02-08 | GSE54798 | GEO