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Effect of HIC1 and miR-212/132 expression on MCF7 cells


ABSTRACT: To identify the target of miR-212, miR-132 and HIC1, we have employed whole genome microarray expression profiling on the human breast cancer MCF7 cells. To generate miR-212/132 or HIC1 inducible MCF7 cells, doxycycline-dependent miR-212/132 or HIC1 gene expression system was used. Either Tet-ON miR-212/132 MCF7 or Tet-ON HIC1 MCF7 were treated with 1μg/ml of Doxycycline for 36 hours with EMEM containing 0.01 mg/ml bovine insulin and 10% FCS. Two independent experiments were performed.

ORGANISM(S): Homo sapiens

SUBMITTER: Yuzawa Yoko 

PROVIDER: S-ECPF-GEOD-37945 | biostudies-other |

REPOSITORIES: biostudies-other

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