Unknown

Dataset Information

0

Expression data from ALK over-expressed MCF-7 clones and control clones


ABSTRACT: To evaluate the function of ALK in breast cancer, we enforcing expressed full length wild type ALK in the parental MCF-7 breast cancer cell line that we have established in previous studies have a very low invasive capacity, do not form tumor emboli nor do they invade into the dermal lymphatics when grown as xenografts. Whole unbiased transcriptome analysis were performed using ALK over-expressed MCF-7 clones and control clones. Pathway mapping revealed that the presence of ALK induced up and down regulation changes of series of genes within several canonical signal pathway.

ORGANISM(S): Homo sapiens

SUBMITTER: Luo Annie 

PROVIDER: S-ECPF-GEOD-41635 | biostudies-other |

REPOSITORIES: biostudies-other

Similar Datasets

2012-10-17 | GSE41635 | GEO
2012-10-17 | E-GEOD-41635 | biostudies-arrayexpress
| S-ECPF-GEOD-57935 | biostudies-other
| S-EPMC9811654 | biostudies-literature
2020-06-01 | MSV000085526 | MassIVE
| S-ECPF-GEOD-46531 | biostudies-other
| S-ECPF-GEOD-39508 | biostudies-other
| S-EPMC9151259 | biostudies-literature
| S-ECPF-GEOD-52674 | biostudies-other
| S-ECPF-GEOD-54439 | biostudies-other