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Expression data from endothelial cells sorted from breast cancer cells MDA-MB231 as compared with normal endothelial cells


ABSTRACT: We studied the crosstalk between tumor and endothelial cells to explore the role of tumor microenvironment on cancer growth and progression. As part of our investigation, we showed that contact-dependent interaction of endothelial cells with breast tumor cells triggered the differential expression of a large number of genes in endothelium. Endothelial and MDA-MB231 cells were co-cultured together under serum- cytokine-free environment for 5 days followed by sorting endothelial cells and extracting RNA for microarray analysis. All conditions were made in triplicate. Endothelial cells were obtained using the methods described in Seandel M. & Butler J.M., 2008. WCMC-Q Genomics Core

ORGANISM(S): Homo sapiens

SUBMITTER: Halabi Najeeb 

PROVIDER: S-ECPF-GEOD-48786 | biostudies-other |

REPOSITORIES: biostudies-other

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