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Effect of catalase inactivation on levels of inorganic peroxides, superoxide dismutase, glutathione, oxygen consumption and life span in adult houseflies (Musca domestica).

ABSTRACT: The effects of total inhibition of catalase, induced by 3-amino-1,2,4-triazole, on the adult housefly (Musca domestica) were examined. The lack of catalase activity had no effect on the longevity of the houseflies. Inorganic-peroxide concentration was elevated at younger ages, but declined in older flies. The rate of oxygen consumption by the flies was greatly decreased and the levels of oxidized as well as reduced glutathione were augmented. Superoxide dismutase activity showed a slight increase. This study suggests that loss of catalase activity does not affect survival of houseflies due to adaptive responses.

SUBMITTER: Allen RG

PROVIDER: S-EPMC1152531 | biostudies-other | 1983 Nov

REPOSITORIES: biostudies-other

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Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity.

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Involvement of catalase and superoxide dismutase in hydrophobic organic solvent tolerance of Escherichia coli.

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2016-08-04 | GSE85160 | GEO

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