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Age- and activity-related changes in three proteinase enzymes of rat skeletal muscle.


ABSTRACT: The specific activities of three proteinases, cathepsins B, D and H, were measured in two skeletal-muscle types as a function of age (i.e. from large foetal life to old age), and in muscles immobilized at various lengths for 3 days. The activities of the lysosomal endopeptidases B and D, but not H, consistently changed in parallel with previously determined rates of protein breakdown, indicating a good and potentially useful correlation between the two.

SUBMITTER: Goldspink DF 

PROVIDER: S-EPMC1152692 | biostudies-other | 1985 Sep

REPOSITORIES: biostudies-other

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