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Structural variations in actins. A study of the immunological reactivity of the N-terminal region.


ABSTRACT: The antigenicity of the N-terminal region of skeletal-muscle actin was analysed. Two epitopes, corresponding to the 1-7 and 18-28 sequences, were determined. The antibodies specific for the first epitope discriminate skeletal-muscle actin from cardiac-muscle and smooth-muscle actins. The antibodies specific for the second epitope interact with all the actins tested, ranging from invertebrate to higher-vertebrate actins.

SUBMITTER: Roustan C 

PROVIDER: S-EPMC1153003 | biostudies-other | 1986 Jan

REPOSITORIES: biostudies-other

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