N-formyl-L-methionine deformylase activity in human leucocytes and platelets.
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ABSTRACT: Extracts of human neutrophils, lymphocytes and platelets enzymically deformylate N-formyl-L-methionine. Enzyme activity is stimulated by Co2+, inhibited by bivalent-cation chelators and unaffected by inhibitors of serine, thiol and carboxyl proteinases. Leucocyte or platelet N-formylmethionine deformylase may be important in modulation of neutrophil responses to chemoattractant formylmethionyl peptides or similar compounds.
SUBMITTER: Ackerman SK
PROVIDER: S-EPMC1161425 | biostudies-other | 1979 Sep
REPOSITORIES: biostudies-other
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