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Can multiple low-density immunoadsorbents and 'negative' distance matrices help predict the three-dimensional structure of any globular protein?


ABSTRACT: Chemical cross-linking of a protein immobilized on multiple, site-specific, monoclonal, chemically modified antibody matrices combined with analysis of data on a distance matrix is likely to yield sufficient positive and 'negative' long-range distance information to help predict the three dimensional structure of any single-chain globular protein.

SUBMITTER: Pillai S 

PROVIDER: S-EPMC1163365 | biostudies-other | 1981 Oct

REPOSITORIES: biostudies-other

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