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The effects of inhibition of fatty acid oxidation in suckling newborn rats.


ABSTRACT: Inhibition of fatty acid oxidation with pent-4-enoate in suckling newborn rats caused a fall in blood [glucose] and blood [ketone bodies] and inhibition of gluconeogenesis from lactate. Glucose utilization was not increased in newborn rats injected with pent-4-enoate. Active fatty acid oxidation appears to be essential to support gluconeogenesis and to maintain normal blood [glucose] in suckling newborn rats.

SUBMITTER: Pegorier JP 

PROVIDER: S-EPMC1165049 | biostudies-other | 1977 Sep

REPOSITORIES: biostudies-other

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