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Action of dimeric hybrids of native and selectively alkylated ribonuclease A on double-stranded ribonucleic acid.


ABSTRACT: The hypothesis that both active sites of dimeric ribonuclease A have to be simultaneously available in order to make the enzyme able to degrade double-stranded RNA is tested with purified hybrid dimers of ribonuclease A and its carboxymethylated derivative. The results obtained support the hypothesis.

SUBMITTER: D'Alessio G 

PROVIDER: S-EPMC1168081 | biostudies-other | 1974 Jul

REPOSITORIES: biostudies-other

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