Ontology highlight
ABSTRACT:
SUBMITTER: Bousquet-Antonelli C
PROVIDER: S-EPMC1170103 | biostudies-other | 1997 Aug
REPOSITORIES: biostudies-other
Bousquet-Antonelli C C Henry Y Y G'elugne J P JP Caizergues-Ferrer M M Kiss T T
The EMBO journal 19970801 15
Eukaryotic rRNAs possess numerous post-transcriptionally modified nucleotides. The most abundant modifications, 2'-O-ribose methylation and pseudouridylation, occur in the nucleolus during rRNA processing. The nucleolus contains a large number of small nucleolar RNAs (snoRNAs) most of which can be classified into two distinct families defined by conserved sequence boxes and common associated proteins. The C and D box-containing snoRNAs are associated with fibrillarin, and most of them function a ...[more]