Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC1171078 | biostudies-other | 1998 Dec
REPOSITORIES: biostudies-other
Li J J Nishizawa K K An W W Hussey R E RE Lialios F E FE Salgia R R Sunder-Plassmann R R Reinherz E L EL
The EMBO journal 19981201 24
A human CD2 cytoplasmic tail-binding protein, termed CD2BP1, was identified by an interaction trap cloning method. Expression of CD2BP1 is restricted to hematopoietic tissue, being prominent in T and natural killer (NK) cells, with long (CD2BP1L) and short (CD2BP1S) variants arising by alternative RNA splicing. Both CD2BP1 molecules are homologous to Schizosaccharomyces pombe cdc15, and include a helical domain, variable length intervening PEST sequence and C-terminal SH3 domain. Although the CD ...[more]