Ontology highlight
ABSTRACT:
SUBMITTER: Knight SW
PROVIDER: S-EPMC1171559 | biostudies-other | 1999 Sep
REPOSITORIES: biostudies-other
The EMBO journal 19990901 17
We have identified a 34 kDa DNA-binding protein with an HU-like activity in the Lyme disease spirochete Borrelia burgdorferi. The 34 kDa protein is translated from an abundant transcript initiated within the gene encoding the A subunit of DNA gyrase. Translation of the 34 kDa protein starts at residue 499 of GyrA and proceeds in the same reading frame as full-length GyrA, resulting in an N-terminal-truncated protein. The 34 kDa GyrA C-terminal domain, although not homologous, substitutes for HU ...[more]