Unknown

Dataset Information

0

The computed distribution of copper(II) and zinc(II) ions among seventeen amino acids present in human blood plasma.


ABSTRACT: The equilibrium distribution of copper(II) and zinc(II) ions among a mixture of 17 amino acids has been computed from stability-constant and blood-plasma-composition data. At pH7.4, 98% of the copper(II) in the simulated plasma solution is co-ordinated to histidine and cystine, predominantly as the mixed-ligand complexes [Cu.His.Cystine](-) and [Cu.H.His.Cystine]. Approximately half of the zinc(II) is co-ordinated to cysteine and histidine, but appreciable complex-formation occurs with most of the other amino acids. Stability constants are given for copper(II) and zinc(II) amino acid complexes, including some mixed-ligand species, at 37 degrees C and I=0.15m.

SUBMITTER: Hallman PS 

PROVIDER: S-EPMC1176604 | biostudies-other | 1971 Feb

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC5748277 | biostudies-literature
| S-EPMC9105653 | biostudies-literature
| S-EPMC8999569 | biostudies-literature
| S-EPMC6844117 | biostudies-literature
| S-EPMC8179462 | biostudies-literature
| S-EPMC6372834 | biostudies-literature
| S-EPMC10406877 | biostudies-literature
| S-EPMC5355962 | biostudies-literature
| S-EPMC9467429 | biostudies-literature
| S-EPMC7105473 | biostudies-literature