Unknown

Dataset Information

0

Cross-linking of erythrocyte membrane proteins by periodate and intramembrane particle distribution.


ABSTRACT: Treatment of isolated human erythrocyte membranes at pH 7.4 with 0.1-0.5 mM-sodium periodate specifically cross-linked some of the spectrin polypeptides. Treatment with 2 mM-periodate resulted in complete cross-linking of spectrin and partial cross-linking of other polypeptides. The latter treatment also caused aggregation of the intramembrane particles made visible by freeze-fracturing. When membranes that had been treated with 2 mM-periodate were depleted of spectrin by treatment with 0.1 mM-EDTA, extensive aggregation of the intramembrane particles occurred.

SUBMITTER: Gahmberg CG 

PROVIDER: S-EPMC1184014 | biostudies-other | 1978 Jun

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC2568988 | biostudies-literature
| S-EPMC1148431 | biostudies-other
| S-EPMC3411782 | biostudies-literature
| S-EPMC1218563 | biostudies-other
| S-EPMC5899466 | biostudies-literature
| S-EPMC5808910 | biostudies-literature
| S-EPMC3183755 | biostudies-literature
| S-EPMC5478345 | biostudies-literature
| S-EPMC2998077 | biostudies-literature
| S-EPMC6048503 | biostudies-literature