The reversibility of the delta8-cholestenol-delta7-cholestenol isomerase reaction in cholesterol biosynthesis.
Ontology highlight
ABSTRACT: The incubation of Delta(7)-cholestenol with a 10000g supernatant or 105000g microsomes in the presence of tritiated water is studied. The reisolated Delta(7)-cholestenol contained up to 0.67g.atom of tritium/mole. This result can best be explained by assuming the reversibility of the reaction Delta(8)-cholestenol right harpoon over left harpoon Delta(7)-cholestenol.
SUBMITTER: Wilton DC
PROVIDER: S-EPMC1184797 | biostudies-other | 1969 Aug
REPOSITORIES: biostudies-other
ACCESS DATA