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Loss of cell-population-density-dependent incorporation of fucose into the lipid fraction of cultured human tumour cells.


ABSTRACT: The incorporation of radioactively labelled fucose into the lipid fraction of cultured normal human cells and several human tumour-cell lines was examined as a function of the cell population density. Normal cells exhibited a density-dependent pattern of incorporation, whereas in tumour cells the radioactivity incorporated was independent of the cell population density. An exception was found among the tumour cells, which suggests a possible correlation between the loss of this marker and the ability to produce tumours.

SUBMITTER: Gacto M 

PROVIDER: S-EPMC1185677 | biostudies-other | 1978 Apr

REPOSITORIES: biostudies-other

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