Ontology highlight
ABSTRACT:
SUBMITTER: Brown JL
PROVIDER: S-EPMC1205404 | biostudies-other | 1993 Apr
REPOSITORIES: biostudies-other
Brown J L JL Kossaczka Z Z Jiang B B Bussey H H
Genetics 19930401 4
Recessive mutations leading to killer resistance identify the KRE9, KRE10 and KRE11 genes. Mutations in both the KRE9 and KRE11 genes lead to reduced levels of (1-->6)-beta-glucan in the yeast cell wall. The KRE11 gene encodes a putative 63-kD cytoplasmic protein, and disruption of the KRE11 locus leads to a 50% reduced level of cell wall (1-->6)-glucan. Structural analysis of the (1-->6)-beta-glucan remaining in a kre11 mutant indicates a polymer smaller in size than wild type, but containing a ...[more]