A single amino acid substitution (Trp(666)-->Ala) in the interbox1/2 region of the interleukin-6 signal transducer gp130 abrogates binding of JAK1, and dominantly impairs signal transduction.
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ABSTRACT:
SUBMITTER: Haan C
PROVIDER: S-EPMC1221146 | biostudies-other | 2000 Jul
REPOSITORIES: biostudies-other
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