Cathepsin-6, a novel cysteine proteinase showing homology with and co-localized expression with cathepsin J/P in the labyrinthine layer of mouse placenta.
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ABSTRACT: A novel cysteine proteinase, cathepsin-6, was isolated by RNA differential display from mouse placenta. Cathepsin-6 showed the highest homology with cathepsin J (same as P) and L. The structural features including the catalytic triad of the C1 proteinase family were well conserved in cathepsin-6. The expression of cathepsin-6 and cathepsin J/P was restricted in labyrinthine trophoblasts of the placenta.
SUBMITTER: Nakajima A
PROVIDER: S-EPMC1221193 | biostudies-other | 2000 Aug
REPOSITORIES: biostudies-other
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