A sigma28-regulated nonflagella gene contributes to virulence of Campylobacter jejuni 81-176.
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ABSTRACT:
SUBMITTER: Goon S
PROVIDER: S-EPMC1346654 | biostudies-other | 2006 Jan
REPOSITORIES: biostudies-other
Publications
A sigma28-regulated nonflagella gene contributes to virulence of Campylobacter jejuni 81-176.
Goon Scarlett S Ewing Cheryl P CP Lorenzo Maria M Pattarini Dawn D Majam Gary G Guerry Patricia P
Infection and immunity 20060101 1
A Campylobacter jejuni 81-176 mutant in Cj0977 was fully motile but reduced >3 logs compared to the parent in invasion of intestinal epithelial cells in vitro. The mutant was also attenuated in a ferret diarrheal disease model. Expression of Cj0977 protein was dependent on a minimal flagella structure. ...[more]
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