Compensatory evolution in the human malaria parasite Plasmodium ovale.
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ABSTRACT:
SUBMITTER: McCutchan TF
PROVIDER: S-EPMC1470707 | biostudies-other | 2004 Jan
REPOSITORIES: biostudies-other
Publications
Compensatory evolution in the human malaria parasite Plasmodium ovale.
McCutchan Thomas F TF Rathore Dharmendar D Li Jun J
Genetics 20040101 1
The fixation of neutral compensatory mutations in a population depends on the effective population size of the species, which can fluctuate dramatically within a few generations, the mutation rate, and the selection intensity associated with the individual mutations. We observe compensatory mutations and intermediate states in populations of the malaria parasite Plasmodium ovale. The appearance of compensatory mutations and intermediate states in P. ovale raises interesting questions about popul ...[more]
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