Ontology highlight
ABSTRACT:
SUBMITTER: Naito Y
PROVIDER: S-EPMC1538817 | biostudies-other | 2006 Jul
REPOSITORIES: biostudies-other
Naito Yuki Y Ui-Tei Kumiko K Nishikawa Toru T Takebe Yutaka Y Saigo Kaoru K
Nucleic acids research 20060701 Web Server issue
siVirus (http://siVirus.RNAi.jp/) is a web-based online software system that provides efficient short interfering RNA (siRNA) design for antiviral RNA interference (RNAi). siVirus searches for functional, off-target minimized siRNAs targeting highly conserved regions of divergent viral sequences. These siRNAs are expected to resist viral mutational escape, since their highly conserved targets likely contain structurally/functionally constrained elements. siVirus will be a useful tool for designi ...[more]