Ontology highlight
ABSTRACT:
SUBMITTER: Luykx P
PROVIDER: S-EPMC1538820 | biostudies-other | 2006 Jul
REPOSITORIES: biostudies-other
Nucleic acids research 20060701 Web Server issue
Nucleosomes, a basic structural unit of eukaryotic chromatin, play a significant role in regulating gene expression. We have developed a web tool based on DNA sequences known from empirical and theoretical studies to influence DNA bending and flexibility, and to exclude nucleosomes. NXSensor (available at http://www.sfu.ca/~ibajic/NXSensor/) finds nucleosome exclusion sequences, evaluates their length and spacing, and computes an 'accessibility score' giving the proportion of base pairs likely t ...[more]