Ontology highlight
ABSTRACT:
SUBMITTER: Canica MM
PROVIDER: S-EPMC163716 | biostudies-other | 1997 Feb
REPOSITORIES: biostudies-other
Caniça M M MM Barthélémy M M Gilly L L Labia R R Krishnamoorthy R R Paul G G
Antimicrobial agents and chemotherapy 19970201 2
IRT-14 (TEM-45) is a new mutant TEM-type beta-lactamase that was isolated from clinical Escherichia coli P37 and that confers resistance to broad-spectrum penicillins with reduced sensitivity to beta-lactamase inhibitors. The MICs of amoxicillin alone and of amoxicillin combined with 2 micrograms of clavulanic acid or 2 micrograms of tazobactam per ml were 4,096, 2,048, and 1,024 micrograms/ml, respectively. The strain was susceptible to cephalosporins, aztreonam, moxalactam, and imipenem. The e ...[more]