Molecular characterization of FrpB, the 70-kilodalton iron-regulated outer membrane protein of Neisseria meningitidis.
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ABSTRACT:
SUBMITTER: Pettersson A
PROVIDER: S-EPMC173590 | biostudies-other | 1995 Oct
REPOSITORIES: biostudies-other
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Molecular characterization of FrpB, the 70-kilodalton iron-regulated outer membrane protein of Neisseria meningitidis.
Pettersson A A Maas A A van Wassenaar D D van der Ley P P Tommassen J J
Infection and immunity 19951001 10
The structural gene encoding the 70-kDa outer membrane protein FrpB of Neisseria meningitidis was cloned and sequenced. A mutant lacking FrpB was constructed. No difference in iron utilization between the mutant and the parental strain was observed. A minor effect of the mutation on serum resistance was observed. A topology model for FrpB in the outer membrane is proposed. ...[more]
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