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Identification of LytSR-regulated genes from Staphylococcus aureus.

ABSTRACT: In this report, the characterization of a Staphylococcus aureus operon containing two LytSR-regulated genes, lrgA and lrgB, is described. Sequence and mutagenesis studies of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin proteins while lrgB may encode a protein having murein hydrolase activity.

SUBMITTER: Brunskill EW 

PROVIDER: S-EPMC178427 | biostudies-other | 1996 Oct

REPOSITORIES: biostudies-other

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Identification of LytSR-regulated genes from Staphylococcus aureus.

Brunskill E W EW   Bayles K W KW  

Journal of bacteriology 19961001 19

In this report, the characterization of a Staphylococcus aureus operon containing two LytSR-regulated genes, lrgA and lrgB, is described. Sequence and mutagenesis studies of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin proteins while lrgB may encode a protein having murein hydrolase activity. ...[more]

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