Ontology highlight
ABSTRACT:
SUBMITTER: Said-Salim B
PROVIDER: S-EPMC145333 | biostudies-literature | 2003 Jan
REPOSITORIES: biostudies-literature
Saïd-Salim B B Dunman P M PM McAleese F M FM Macapagal D D Murphy E E McNamara P J PJ Arvidson S S Foster T J TJ Projan S J SJ Kreiswirth B N BN
Journal of bacteriology 20030101 2
Staphylococcus aureus produces a wide array of cell surface and extracellular proteins involved in virulence. Expression of these virulence factors is tightly controlled by numerous regulatory loci, including agr, sar, sigB, sae, and arl, as well as by a number of proteins with homology to SarA. Rot (repressor of toxins), a SarA homologue, was previously identified in a library of transposon-induced mutants created in an agr-negative strain by screening for restored protease and alpha-toxin. To ...[more]