Cloning of the gene encoding Streptococcin A-FF22, a novel lantibiotic produced by Streptococcus pyogenes, and determination of its nucleotide sequence.
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ABSTRACT:
SUBMITTER: Hynes WL
PROVIDER: S-EPMC182197 | biostudies-other | 1993 Jun
REPOSITORIES: biostudies-other
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Cloning of the gene encoding Streptococcin A-FF22, a novel lantibiotic produced by Streptococcus pyogenes, and determination of its nucleotide sequence.
Hynes W L WL Ferretti J J JJ Tagg J R JR
Applied and environmental microbiology 19930601 6
Streptococcin A-FF22 (SA-FF22) is a lantibiotic produced by Streptococcus pyogenes FF22. The nucleotide sequence of the SA-FF22 structural gene (scnA) was determined and shown to encode a 51-amino-acid prepeptide. The proteolytic processing site of the SA-FF22 prepeptide differs from that which characterizes other type A lantibiotics. ...[more]
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