Cytopathogenicity of classical swine fever virus caused by defective interfering particles.
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ABSTRACT:
SUBMITTER: Meyers G
PROVIDER: S-EPMC189084 | biostudies-other | 1995 Jun
REPOSITORIES: biostudies-other
Publications
Cytopathogenicity of classical swine fever virus caused by defective interfering particles.
Journal of virology 19950601 6
For three independent cytopathogenic isolates of classical swine fever virus, defective RNAs were found in infected cells in addition to full-length viral genomes. These RNAs represent the genomes of typical defective interfering (DI) particles because of strict dependence on a complementing helper virus and interference with the replication of the helper virus. Analysis of the DI genomes revealed internal deletions of 4,764 nucleotides encompassing the complete structural protein-coding region ...[more]
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