Ontology highlight
ABSTRACT:
SUBMITTER: Slepchenko BM
PROVIDER: S-EPMC2080897 | biostudies-other | 2007 Nov
REPOSITORIES: biostudies-other
Slepchenko Boris M BM Semenova Irina I Zaliapin Ilya I Rodionov Vladimir V
The Journal of cell biology 20071112 4
Intracellular transport of membrane organelles occurs along microtubules (MTs) and actin filaments (AFs). Although transport along each type of the cytoskeletal tracks is well characterized, the switching between the two types of transport is poorly understood because it cannot be observed directly in living cells. To gain insight into the regulation of the switching of membrane organelles between the two major transport systems, we developed a novel approach that combines live cell imaging with ...[more]