Ontology highlight
ABSTRACT:
SUBMITTER: Hourcade D
PROVIDER: S-EPMC2189081 | biostudies-other | 1988 Oct
REPOSITORIES: biostudies-other
Hourcade D D Miesner D R DR Atkinson J P JP Holers V M VM
The Journal of experimental medicine 19881001 4
The human C3b/C4b receptor or complement receptor type one (CR1) is an approximately 200-kD single chain membrane glycoprotein of human peripheral blood cells that mediates the binding, processing, and transport of C3b-bearing immune complexes and regulates the activity of the complement cascade. Analysis of partial cDNA clones has shown that the COOH terminus is composed predominantly of three tandemly repeated regions of 450 amino acids each (15). In this report, we present a cDNA sequence tha ...[more]