Ontology highlight
ABSTRACT:
SUBMITTER: Cherayil BJ
PROVIDER: S-EPMC2189532 | biostudies-other | 1989 Dec
REPOSITORIES: biostudies-other
Cherayil B J BJ Weiner S J SJ Pillai S S
The Journal of experimental medicine 19891201 6
A cDNA encoding the Mac-2 antigen, a surface marker highly expressed by thioglycollate-elicited macrophages, has been cloned by immunoscreening of a lambda gt11-P388D1 expression library. The nucleotide sequence of the cDNA is identical to that of carbohydrate-binding protein 35, a galactose-specific lectin found in fibroblasts and highly homologous to a rat IgE-binding protein from basophilic leukemia cells. The in vitro synthesized Mac-2 protein displayed the expected carbohydrate- and IgE-bin ...[more]