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Mechanisms of resistance to daptomycin in Enterococcus faecium.


ABSTRACT: In this study, we investigated the clonal emergence of daptomycin-resistant Enterococcus faecium strains isolated from a patient with leukocyte adhesion deficiency syndrome. The resistance mechanism in these strains is independent of either equivalent point mutations previously described for Staphylococcus aureus or daptomycin inactivation mechanisms identified in soil bacteria.

SUBMITTER: Montero CI 

PROVIDER: S-EPMC2258551 | biostudies-other | 2008 Mar

REPOSITORIES: biostudies-other

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Mechanisms of resistance to daptomycin in Enterococcus faecium.

Montero Clemente I CI   Stock Frida F   Murray Patrick R PR  

Antimicrobial agents and chemotherapy 20080107 3


In this study, we investigated the clonal emergence of daptomycin-resistant Enterococcus faecium strains isolated from a patient with leukocyte adhesion deficiency syndrome. The resistance mechanism in these strains is independent of either equivalent point mutations previously described for Staphylococcus aureus or daptomycin inactivation mechanisms identified in soil bacteria. ...[more]

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