Ontology highlight
ABSTRACT:
SUBMITTER: Sinha AU
PROVIDER: S-EPMC2289817 | biostudies-other | 2008 Feb
REPOSITORIES: biostudies-other
Sinha Amit U AU Kaimal Vivek V Chen Jing J Jegga Anil G AG
BMC genomics 20080223
<h4>Background</h4>The master regulator p53 tumor-suppressor protein through coordination of several downstream target genes and upstream transcription factors controls many pathways important for tumor suppression. While it has been reported that some of the p53's functions are microRNA-mediated, it is not known as to how many other microRNAs might contribute to the p53-mediated tumorigenesis.<h4>Results</h4>Here, we use bioinformatics-based integrative approach to identify and prioritize putat ...[more]