The pseudorabies virus homology of the herpes simplex virus UL21 gene product is a capsid protein which is involved in capsid maturation.
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ABSTRACT:
SUBMITTER: de Wind N
PROVIDER: S-EPMC240387 | biostudies-other | 1992 Dec
REPOSITORIES: biostudies-other
Publications
The pseudorabies virus homology of the herpes simplex virus UL21 gene product is a capsid protein which is involved in capsid maturation.
de Wind N N Wagenaar F F Pol J J Kimman T T Berns A A
Journal of virology 19921201 12
We mutagenized, mapped, and sequenced the pseudorabies virus (PRV) homology of gene UL21 of herpes simplex virus type 1. A polyclonal mouse antiserum against the protein encoded by the UL21 homolog was generated and used to monitor the expression and subcellular localization of the UL21-encoded protein. We found that the protein is identical to a previously detected PRV capsid protein. We analyzed viable PRV strains encoding mutant UL21 homologys, truncated by insertion of an oligonucleotide tha ...[more]
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