Ontology highlight
ABSTRACT:
SUBMITTER: Beausang JF
PROVIDER: S-EPMC2599829 | biostudies-other | 2008 Dec
REPOSITORIES: biostudies-other
Beausang John F JF Schroeder Harry W HW Nelson Philip C PC Goldman Yale E YE
Biophysical journal 20081017 12
The force generated between actin and myosin acts predominantly along the direction of the actin filament, resulting in relative sliding of the thick and thin filaments in muscle or transport of myosin cargos along actin tracks. Previous studies have also detected lateral forces or torques that are generated between actin and myosin, but the origin and biological role of these sideways forces is not known. Here we adapt an actin gliding filament assay to measure the rotation of an actin filament ...[more]