Evidence of pestivirus RNA in human virus vaccines.
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ABSTRACT:
SUBMITTER: Harasawa R
PROVIDER: S-EPMC264050 | biostudies-other | 1994 Jun
REPOSITORIES: biostudies-other
Publications
Evidence of pestivirus RNA in human virus vaccines.
Journal of clinical microbiology 19940601 6
We examined live virus vaccines against measles, mumps, and rubella for the presence of pestivirus RNA or of pestiviruses by reverse transcription PCR. Pestivirus RNA was detected in two measles-mumps-rubella combined vaccines and in two monovalent vaccines against mumps and rubella. Nucleotide sequence analysis of the PCR products indicated that a modified live vaccine strain used for immunization of cattle against bovine viral diarrhea is not responsible for the contamination of the vaccines. ...[more]
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