RNA-directed DNA methylation requires an AGO4-interacting member of the SPT5 elongation factor family.
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ABSTRACT:
SUBMITTER: Bies-Etheve N
PROVIDER: S-EPMC2711833 | biostudies-other | 2009 Jun
REPOSITORIES: biostudies-other
Publications
RNA-directed DNA methylation requires an AGO4-interacting member of the SPT5 elongation factor family.
Bies-Etheve Natacha N Pontier Dominique D Lahmy Sylvie S Picart Claire C Vega Danielle D Cooke Richard R Lagrange Thierry T
EMBO reports 20090403 6
Recent studies have identified a conserved WG/GW-containing motif, known as the Argonaute (AGO) hook, which is involved in the recruitment of AGOs to distinct components of the eukaryotic RNA silencing pathways. By using this motif as a model to detect new components in plant RNA silencing pathways, we identified SPT5-like, a plant-specific AGO4-interacting member of the nuclear SPT5 (Suppressor of Ty insertion 5) RNA polymerase (RNAP) elongation factor family that is characterized by the presen ...[more]
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