Ontology highlight
ABSTRACT:
SUBMITTER: Saneyoshi H
PROVIDER: S-EPMC2765511 | biostudies-other | 2008 Dec
REPOSITORIES: biostudies-other
The Journal of organic chemistry 20081201 23
Conformationally locked North and South versions of puromycin analogues built on a bicyclo[3.1.0]hexane pseudosugar template were synthesized. The final assembly of the products was accomplished by the Staudinger-Vilarrasa coupling of the corresponding North (2 and 3) and South (6 and 7) 3'-azidopurine carbanucleosides with the Fmoc-protected 1-hydroxybenzotriazole ester of 4-methoxy-L-tyrosine. North azides 2 and 3 were reported earlier. The 3'-azido intermediates 6 and 7 that are necessary for ...[more]