Ontology highlight
ABSTRACT:
SUBMITTER: Yu H
PROVIDER: S-EPMC2769491 | biostudies-other | 2007 Aug
REPOSITORIES: biostudies-other
Organic & biomolecular chemistry 20070627 15
Sialyl Tn (STn) and sialyl lactoside derivatives containing O-acetylated sialic acid residues have been chemoenzymatically synthesized using a one-pot three-enzyme system and conjugated to biotinylated human serum albumin (HSA) using an adipic acid para-nitrophenyl ester coupling reagent. This approach provides an efficient and general protocol for preparing carbohydrate-protein conjugates containing base-sensitive groups. ...[more]