The RESA-2 gene of Plasmodium falciparum is transcribed in several independent isolates.
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ABSTRACT:
SUBMITTER: Vazeux G
PROVIDER: S-EPMC281181 | biostudies-other | 1993 Oct
REPOSITORIES: biostudies-other
Publications
The RESA-2 gene of Plasmodium falciparum is transcribed in several independent isolates.
Vazeux G G Le Scanf C C Fandeur T T
Infection and immunity 19931001 10
The relevance of the ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum as a malaria vaccine candidate has been questioned of late because RESA-deficient parasites have been found to multiply normally in culture or in monkeys. The RESA-2 gene was recently described as a pseudogene highly homologous to RESA. In this report, we demonstrate that RESA-2 is not a pseudogene, because we were able to detect RESA-2 transcripts in asexual blood stages of multiple isolates by using ...[more]
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