Ontology highlight
ABSTRACT:
SUBMITTER: Ozlu N
PROVIDER: S-EPMC2830844 | biostudies-other | 2010 Feb
REPOSITORIES: biostudies-other
Molecular & cellular proteomics : MCP 20090928 2
The cytoskeleton globally reorganizes between mitosis (M phase) and cytokinesis (C phase), which presumably requires extensive regulatory changes. To reveal these changes, we undertook a comparative proteomics analysis of cells tightly drug-synchronized in each phase. We identified 25 proteins that bind selectively to microtubules in C phase and identified several novel binding partners including nucleolar and spindle-associated protein. C phase-selective microtubule binding of many of these pro ...[more]