Ontology highlight
ABSTRACT:
SUBMITTER: Malhotra R
PROVIDER: S-EPMC2854872 | biostudies-other | 2010 Apr
REPOSITORIES: biostudies-other
Malhotra Ruchika R Patel Vyomesh V Vaqué Jose Pedro JP Gutkind J Silvio JS Rusling James F JF
Analytical chemistry 20100401 8
Squamous cell carcinomas of head and neck (HNSCC) are associated with immune, inflammatory, and angiogenic responses involving interleukin-6 (IL-6). This article reports an ultrasensitive electrochemical immunosensor for human IL-6 and proof-of-concept studies of IL-6 detection in HNSCC cells. Single wall carbon nanotube (SWNT) forests with attached capture antibodies (Ab(1)) for IL-6 were used in an electrochemical sandwich immunoassay protocol using enzyme label horseradish peroxidase (HRP) to ...[more]